ATLUS HEAMATOLOGY

ERYTHROPOIESIS Erythropoiesis constitute 10-30% of hemopoietic cells in the bone marrow. The mature erythrocyte is derived from the stem cell, which differentiate to erythroid colony forming cells (BFU-E, CFU-E), and next to the proerythroblast, the first morphologically recognizable cell of the series. The proerythroblast matures to the basophilic normoblast, then the polichromatic normoblast, where synthesis of hemoglobin is started. At the end, the polychromatophilic normoblast matures to the orthochromatic normoblast. The orthochromatic normoblast loses its nucleus and developes into reticulocyte, which after 2-4 days develops into mature erythrocyte. The mature erythrocyte stays for ca. 4 months in the blood.
Proerythroblasts	Basophilic (early) normoblast
Polychromatic (intermediate) normoblas	Pycnotic (late) normoblast
Reticulocytes	Normocytes
Microcytes	Macrocytes
Megalocytes	Anisocytosis
Hypochromia	Polychromasia
Eliptocytes	Lacrymocytes
Target cells	Acanthocytes
Echinocytes	Crenated red blood cells
Schistocytes	Stomatocytes
Spherocytes	Leptocytes
Anulocytes	Sickle cells
Poikilocytosis	Howell-Jolly bodies
Cabot rings	Basophilic stippling
Pappenheimer bodies	Normoblasts in blood